Clinical Research

Clinical Studies

With the potential and regulatory approval for a broad range of use cases, our research partners are investigating and delivering the body of scientific evidence to support clinical applications and benefits to patients with various lung conditions.

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CLINICAL TRIALS

Study type:
Interventional (Clinical Trial)
Current Stage:
Final Imaging

4DX Functional Lung Imaging in the Diagnosis of Chronic Lung Allograft Dysfunction After Lung Transplantations

estimated enrollment:
15 Participants
Observation model:
TIME Perspective:

estimated enrollment:

15 Participants

Observation model:

TIME Perspective:

Masking:

None (Open Label)

Primary Purpose:

Diagnostic

Interventional Model:

Parallel Assignment

Interventional Model Description:

4DxXV Ventilation Analysis applied to flouroscopic images

This is a pilot study to determine the utility of Novel Functional Lung Imaging and Ventilation (4DxV) Analysis software in measurement of lung ventilation abnormalities and diagnosis of chronic lung allograft dysfunction (CLAD) after lung transplantation.

Study type:
TBC
Current Stage:
Patient Recruitment

4DXV for Targeting in Broncoscopic Lung Volume Reduction

estimated enrollment:
50 Participants
Observation model:
Case-control
TIME Perspective:
Prospective

estimated enrollment:

50 Participants

Observation model:

Case-control

TIME Perspective:

Prospective

Masking:

Primary Purpose:

Interventional Model:

Interventional Model Description:

This study will investigate the utility of 4D Medical’s X-ray Velocimetry (XV) imaging analysis software for the detection of hyperinflation, and compare endobronchial valve placement outcomes with predictive indices obtained utilizing this technique.

Study type:
Observational
Current Stage:
Patient Recruitment

Ventilation Imbalances in Mild to Moderate Chronic Obstructive Pulmonary Disease (VAPOR)

estimated enrollment:
15 Participants
Observation model:
Case-only
TIME Perspective:
Prospective

estimated enrollment:

15 Participants

Observation model:

Case-only

TIME Perspective:

Prospective

Masking:

Primary Purpose:

Interventional Model:

Interventional Model Description:

The Investigators plan a single center study to get preliminary data to answer a number of fundamental questions directly related to management of COPD.

The research will determine whether ventilation heterogeneity and distribution of ventilation inform, determine, assist or drive the: 1) status or clinical course in patients with COPD, 2) understanding of factors associated with activities of daily living and quality of life in patients, 3) risk of exacerbation or hospitalization in those with COPD, and 4) predictors of therapeutic pathway or treatment regime.

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